E F Sarkisova

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The morpho-functional development of the visual area of the cerebral cortex of newborn rats and effects of serotonin (5-HT) on these processes were studied in long-term (up to 40 days) organotypic cultures. It was shown that systematic addition of 5-HT in physiological concentrations to the nutrient medium during cultivation of the explants stimulates glia(More)
The paper deals with morpho-functional development of the visual area of newborn rats cerebral cortex in conditions of prolonged (up to 40 days) organotypical cultivation and with the effect of serotonin (5-OT) on these processes. It has been shown that systematic addition of physiological concentrations of 5-OT to the nutrient medium during explantates(More)
The influence of noradrenaline (NA) on the functional development and chemical sensitivity of neurons of the newborn rat hippocamp was studied in organotypic cultures during the period of up to 38 days. NA was shown to inhibit the formation of spontaneous activity and lessen the number of active neurons in the explants. In these cultures, like in hippocamp(More)
Morpho-functional development of the raphe nuclei neurons was studied in long-term (up to 20 days) organotypic cultures taken from newborn rats. Differentiated neurons typical for raphe nuclei were identified in explants after 10 days in vitro. The synthesis of serotonin (5-HT) and uptake of 3H-5-HT were more intense in the raphe neurons culture than in(More)
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