Familial hemiplegic migraine (FHM) is an autosomal dominant disorder characterized by transient hemiplegia during the aura phase of a migraine attack. Nystagmus has been reported in individuals affected with this disorder, but the origin of the ocular motility findings is unknown. A three-generation family with FHM is described and clinical histories are… (More)
A patient received an overdose of intravascular contrast medium and experienced protracted seizures associated with radiographic evidence of prolonged retention of the contrast agent in the cerebral cortex, basal ganglia, and thalami. This is only the second report and the first survivor of a similar neurologic syndrome occurring in a patient after contrast… (More)
A patient is described who developed seesaw nystagmus (SSN) associated with progressive severe vision loss due to cone-rod dystrophy. She was otherwise neurologically normal, and findings on magnetic resonance imaging of the brain were normal, including optic chiasm, meso-diencephalic junction, and brainstem. The literature is reviewed on neurologically… (More)
Spectroscopy has an illustrious history delivering serendipitous discoveries and providing a stringent testbed for new physical predictions, including applications from trace materials detection, to understanding the atmospheres of stars and planets, and even constraining cosmological models. Reaching fundamental-noise limits permits optimal extraction of… (More)
This report describes two unusual cases of parasellar arachnoid cyst with different neuro-ophthalmologic manifestations and clinical courses: a 33-year-old woman with parasellar arachnoid cyst, manifested by incongruous homonymous hemianopia, and a 64-year-old man with a presumed parasellar arachnoid cyst and bitemporal hemianopia that subsequently… (More)
Erythromycin is not currently recognized as causing clinical aggravation of myasthenia gravis. We report the case of a patient who experienced exacerbations of myasthenia gravis subsequent to each of several doses of intravenous erythromycin. We suggest that erythromycin can cause clinical worsening in patients with disease of the neuromuscular junction.