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Multiple sclerosis in Gypsies from southern Spain: prevalence, mitochondrial DNA haplogroups and HLA class II association.

• Oscar Fernández, Val Fernández, +9 authors Laura Alvarado Leyva
• Tissue antigens
• 2008

Occasional reports have mentioned the prevalence of multiple sclerosis (MS) among Gypsies, and no studies have examined to date the prevalence of MS or human leukocyte antigen (HLA) genetics… (More)

Normalización y validación de la batería neuropsicológica breve como test neuropsicológico de referencia en la esclerosis múltiple

• Jordi Ibáñez Nolla, Oscar Fernández, +4 authors Grupo Bnbem
• 2012

Natural evolution of skin test sensitivity in patients allergic to beta-lactam antibiotics.

• Miguel Blanca, Maria J Torres, +6 authors Carlos Miguel Salazar Juárez
• The Journal of allergy and clinical immunology
• 1999

BACKGROUND Subjects with immediate reactions to penicillins and positive skin test responses may lose sensitivity if penicillin is avoided. The longer the interval between the reaction and the skin… (More)

Probing the mechanism of Bacillus 1,3-1,4-beta-D-glucan 4-glucanohydrolases by chemical rescue of inactive mutants at catalytically essential residues.

• Joseph Luis Viladot, E De Ramón, Olga Durany, Antoni Planas
• Biochemistry
• 1998

The role of the key catalytic residues Glu134 and Glu138 in the retaining 1,3-1,4-beta-glucanase from Bacillus licheniformis is probed by a chemical rescue methodology based on enzyme activation of… (More)

Azathioprine and methotrexate in multiple sclerosis

• Oscar Fernández, Victoria Fernández, E De Ramón
• Journal of the Neurological Sciences
• 2004

Evidence for the effectiveness of immunosuppressive agents in MS is scanty. There are few good quality trials; most have methodological limitations, such as a small sample size and short duration.… (More)

Multiple sclerosis prevalence in Malaga, Southern Spain estimated by the capture-recapture method.

• Oscar Fernández, Victoria E Fernández, +14 authors E De Ramón
• Multiple sclerosis
• 2012

BACKGROUND Although not definitively proven, there is commonly accepted to be a latitudinal gradient in the distribution of multiple sclerosis (MS), which is more frequent in temperate zones. The… (More)

HLA class II and response to interferon-beta in multiple sclerosis.

• Oscar Fernández, Val Fernández, +8 authors E De Ramón
• Acta neurologica Scandinavica
• 2005

OBJECTIVE To study the relationship between human leucocyte antigen (HLA) genotype and clinical response to interferon-beta (IFN-beta). METHODS We analysed the HLA class II genotypes of 96 multiple… (More)

Determination of IgE antibodies to the benzylpenicilloyl determinant: a comparison of the sensitivity and specificity of three radio allergo sorbent test methods.

• José Javier Echeverría García, Miguel Blanca, +6 authors E De Ramón
• Journal of clinical laboratory analysis
• 1997

The quantitation of in vitro IgE antibodies to the benzylpenicilloyl determinant (BPO) is a useful tool for evaluating suspected penicillin allergic subjects. Although many different methods have… (More)

Clinical benefits of interferon beta-1a in relapsing-remitting MS: a phase IV study.

• Oscar Fernández, Tx. Arbizu, +4 authors E De Ramón
• Acta neurologica Scandinavica
• 2003

OBJECTIVE To evaluate the efficacy and safety of IFNbeta-1a (Avonex, Biogen, Inc., Cambridge, MA, USA) in patients with relapsing-remitting multiple sclerosis (MS). METHODS In this multicenter,… (More)

The efficacy of natalizumab in patients with multiple sclerosis according to level of disability: results of an observational study.

• Oscar Fernández, Marcos Papais Alvarenga, +8 authors Victoria E Fernández
• Multiple sclerosis
• 2011

BACKGROUND Little is known about how the level of disability at the start of treatment with natalizumab affects its efficacy. OBJECTIVES The aim of this study was to investigate the effect of… (More)

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