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Pharmacokinetics of 3'-fluoro-3'-deoxythymidine and 3'-deoxy-2',3'-didehydrothymidine in rats.

• F. Douglas Boudinot, S. G. Smith, E D Funderburg, Rinaldo Schinazi
• Antimicrobial agents and chemotherapy
• 1991

Concentrations of 3'-fluoro-3'-deoxythymidine (FDT) and 3'-deoxy-2',3'-didehydrothymidine (D4T) in plasma declined in a biexponential fashion. Total clearance of D4T (1.75 +/- 0.22 liters/h/kg; mean… (More)

Effects of age on the pharmacokinetics of piroxicam in rats.

• Sally Boudinot, E D Funderburg, F. Douglas Boudinot
• Journal of pharmaceutical sciences
• 1993

This study examined the effects of age on the pharmacokinetics of piroxicam in rats. Two groups of rats, aged 5 and 24 months, were administered 1 mg of piroxicam per kg intravenously, and blood… (More)

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