E Balaguer

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INTRODUCTION Currently used antiparkinsonian drugs neither stop nor slow-down the progressive nature of the disease. The final phase of PD is characterized by the presence of symptoms and signs resistant to dopaminergic agents, such as depression, dementia, freezing and falls. Therefore, it is urgent to develop therapies able to positively modify this(More)
acrjourna bal downregulation of microRNAs (miRNA) is a common feature in colorectal cancer (CRC). Whereas sland hypermethylation constitutes a mechanism for miRNA silencing, this field largely remains uned. Herein, we describe the epigenetic regulation of miR-137 and its contribution to colorectal carcinos. We determined the methylation status of miR-137(More)
nloaded bal downregulation of microRNAs (miRNA) is a common feature in colorectal cancer (CRC). Whereas sland hypermethylation constitutes a mechanism for miRNA silencing, this field largely remains uned. Herein, we describe the epigenetic regulation of miR-137 and its contribution to colorectal carcinos. We determined the methylation status of miR-137 CpG(More)
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