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Computational challenges for computer scientists in the task of determining the structure of molecules and their components are examined. Problems in sequence analysis, information storage and retrieval and protein structure prediction are summarized. A brief overview of molecular biology provides some context for the problems described.<<ETX>>
Three children with rhabdomyosarcoma of the prostate treated with combination chemotherapy and radiation therapy underwent radical extirpation with continent diversion to the urethra. This urological procedure is technically feasible even in the small child (2 years old) and offers chance for cure. Radical cystectomy with continent diversion need not be(More)
cave bear and known Neanderthal genomic sequences using direct genomic selection indicates that this is a feasible strategy for purifying specific cloned Neanderthal sequences out of a high background of Neanderthal and contaminating microbial DNA. This raises the possibility that, should multiple Neanderthal metagenomic libraries be constructed from(More)
Fabre has previously questioned the rat kidney allograft model from an immunologic perspective and raised some important considerations. The present study addresses further the fidelity of the rat renal allograft model from a physiologic rather than immunologic perspective. We reviewed several rat renal allograft studies from several laboratories, including(More)
Description The data contains a list with three elements: breast, prostate and map. The first two are expression sets of class ExpressionSet taken from the breast cancer study of Huang et al. (2003) and the prostate cancer study of Singh et al. (2002). Both data sets were preprocessed as described in Yang et al. (2006). The data sets serve as illustration(More)
Gross hemoglobinuria following mitral valve replacement can represent a rare form of hemolytic anemia. This condition can masquerade as gross hematuria in the post-valve replacement patient. It is commonly associated with valvular dysfunction, specifically, perivalvular leakage. The leakage may not be apparent on routine echocardiography but it may be(More)
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