E. A. Fernandez

Learn More
Many physiologic differences between children and adults may result in age-related changes in pharmacokinetics and pharmacodynamics. Factors such as gastric pH and emptying time, intestinal transit time, immaturity of secretion and activity of bile and pancreatic fluid among other factors determine the oral bioavailability of pediatric and adult(More)
BACKGROUND Grasses and olive trees are the most common sources of allergenic pollen worldwide. Although they share some allergens, there are few studies analyzing the in vitro cross-reactivity between them. The aim was to define the cross-reactivity between Olea europaea and Phleum pratense using well-characterized sera of allergic children from Madrid,(More)
(Ambrosia artemi-siifolia) pollen were investigated by mass spectrometry (MS), 2D-PAGE and immunoblotting. Furthermore, Amb a 1 isoallergens were purified and IgE reactivity determined by immunoblotting and IgE inhibition. Results: 2D-PAGE and MS of ragweed extract proved the presence of all 5 known Amb a 1 isoallergens, of which Amb a 1.01 represents the(More)
The hay may be responsible for developing food allergy to plants. The geographical and climatological condition of Querétaro city, and having a large industrial corridor are risk factors for development allergic problems. In Mexico there are no prevalence studies on food allergy and therefore the most common food allergens. The objectives of the study are(More)
Two protocols (ie, preventive and therapeutic protocol) were designed to evaluate the effects of LTS61K in Der p sensitized and challenged mouse model of asthma. Results: Both intranasal inoculations with LTS61K or LTS61K/Der p decreased allergen-induced airway inflammation and alleviated systemic T H 2-type immune response. In addition, bronchoalveolar(More)
Science Fund shows for the first time that the allergen uptake is specific and similar in DCs from allergic and healthy individuals. More important, the ensuing signal cascade that is triggered by the allergen differs between DCs of the 2 donor groups and results in a Th2-polarized immune response in allergic individuals as compared to ignorance/tolerance(More)
  • 1