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Great Lakes (GL) sport fish consumption is a potential route of exposure for environmentally persistent organochlorine contaminants, which may have human health effects. In this report, relationships are explored among individual congeners in a large cohort of frequent and infrequent GL sport fish consumers. Blood samples were obtained in 1993-1995 and(More)
This study investigated the relationships of steroid and thyroid hormones with total noncoplanar polychlorinated biphenyls (PCBs), total toxic equivalents (TEQs) from dioxins-like organochlorines, and dichlorodiphenyl dichloroethene (DDE) in 56 male frequent and infrequent Great Lakes sport caught fish consumers. Significant negative associations were found(More)
Cross-sectional surveys of human blood and breast milk show increasing concentrations of polybrominated diphenyl ethers (PBDEs) that parallel the expanded use in consumer products, but longitudinal studies are lacking. We compared levels of major BDE congeners in archived 1994-1995 blood samples collected from a cohort of frequent and infrequent Great Lakes(More)
Many popular varieties of commercially sold fish, including tilefish, seabass, shark, and swordfish, contain enough mercury so that eating them once or twice a month can lead to high mercury body burdens. Wisconsin has issued mercury-based sport-fish consumption advice to people of all ages since 1985. Wisconsin's advisory was revised in 2000 to address all(More)
Previous studies have suggested that exposure to polychlorinated biphenyls (PCBs) may alter thyroid function, but data on effects of PCB exposure on other endogenous hormones has been lacking. The current study is ancillary to a larger investigation of the effects of Great Lakes fish consumption on PCBs and reproductive function. In the current study we(More)
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