Dustin H. Hardwick

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STUDY DESIGN Single-group repeated-measures design. OBJECTIVES To investigate the ability of the wall slide exercise to activate the serratus anterior muscle (SA) at and above 90 degrees of humeral elevation. BACKGROUND Strengthening of the SA is a critical component of rehabilitation for patients with shoulder impingement syndromes. Traditional SA(More)
Stimulation of intact platelets by ADP results in a shape change followed by aggregation in the presence of fibrinogen. ADP was found to induce a shape change in chymotrypsin-treated platelets that was similar in extent and initial velocity to that of intact (untreated) platelets. Scanning-electron microscopy verified an ADP-induced shape change in(More)
Cholera toxin (CT) elicits a dosage-dependent increase in mucin secretion by explants of guinea pig trachea. Concomitantly, the mucin in goblet cells of the mucosa and submucosal glands is depleted. This effect is realized in the absence of cell injury, as assessed morphologically and by the assay of culture medium for the release of acid phosphatase.(More)
Study Design: Single-group repeated-measures design. Objectives: To investigate the ability of the wall slide exercise to activate the serratus anterior muscle (SA) at and above 90° of humeral elevation. Background: Strengthening of the SA is a critical component of rehabilitation for patients with shoulder impingement syndromes. Traditional SA exercises(More)
In order to study specific anatomical relationships among organelles involved in the movement and secretion of mucin granules by airway epithelium, a three-dimensional replica of a single goblet cell from porcine trachea was constructed by means of transmission electron microscopy of serially prepared ultrathin sections. Many features of the goblet cell(More)
PAF-acether, a naturally occurring phospholipid, is a potent activator of various biological processes, including platelet aggregation. The mechanisms of action of PAF are largely unknown. We have found that the psychotropic triazolobenzodiazepine drugs, alprazolam and triazolam, potently (IC50 less than 1 microM) inhibit PAF-induced shape change,(More)
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