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We have identified a new role for the matrix enzyme lysyl oxidase–like-2 (LOXL2) in the creation and maintenance of the pathologic microenvironment of cancer and fibrotic disease. Our analysis of… Expand
1,4-Butanediol (BD) is converted to gamma-hydroxybutyrate (GHB) after ingestion, and is associated with cases of dependence, coma, and death. The pharmacology of BD after oral ingestion has not been… Expand
Background: Gamma-hydroxybutyrate (GHB) is a common drug of abuse that can produce serious toxicity, particularly when used with other sedatives. We examined the individual and combined effects of… Expand
Gamma-hydroxybutyric acid (GHB) is used as an illicit drug and is implicated in drug-facilitated sexual assault, but it also has some therapeutic uses. Detection of GHB in urine is important for… Expand
Background: Simtuzumab (SIM) is a humanized monoclonal antibody that inhibits lysyl oxidase-like molecule 2 (LOXL2), an extracellular matrix enzyme that catalyzes the covalent cross-linking of… Expand
75Background: Andecaliximab (ADX) is a monoclonal antibody that inhibits matrix metalloproteinase 9 (MMP9). Preclinical studies suggest that MMP9 inhibition relieves immune suppression and promotes… Expand
A citation graph is an important part of modern scientometrics (the field of analyzing and measuring of scientific literature) [2–19,21,23–31]. To construct it, we need to disambiguate citations:… Expand
Accurate parsing of citation reference strings is crucial to automatically construct scholarly databases such as Google Scholar or Semantic Scholar. Citation field extraction (CFE) is precisely this… Expand
207Background: Blood-based tests can predict drug response and disease progression. Many tests rely on detecting tumor DNA, which represents only a fraction of all cell-free DNA (cfDNA). Here, we u...