Duncan T. T. Lin

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To study the effect of surface properties on the biocompatibility of biomaterials based on the same material, polyurethane membranes with different surface properties were prepared. Myoblast culture and interleukin-1 (IL-1) generation in an air pouch model and in vitro monocyte culture were used to examine biocompatibility of different polyurethane(More)
This study evaluated the effects of crystalline polyamide (Nylon-66), poly(ethylene-co-vinyl alcohol) (PEVA), and poly(vinylidene fluoride) (PVDF) polymers with nonporous and porous morphologies on the ability of monocytes to adhere and subsequently activate to produce IL-1beta, IL-6, and tumor necrosis factor alpha. The results indicated monocyte adhesion(More)
To fully interpret the Ronchigram, a good automatic phase reduction algorithm is necessary. A new phase reduction algorithm, originally designed for interferometry test of large optics, is presented for the Ronchi test. Due to the common path property, only two Ronchigrams shifted by pi/2 are necessary for the reproducing phase. Accuracy can be better than(More)
The relative toxicity of 20 ortho-, meta-, and para-position monoalkylated or monohalogenated benzyl alcohols has been determined as 50% population growth inhibition (log BR; biological response) to Tetrahymena pyriformis. Linear relationships are observed between log BR and the 1-octanol/water partition coefficient (log Kow) for both the alkylated and the(More)
Eighty 2-, 3-, and 4-position monosubstituted phenols representing various substituents were evaluated for relative toxicity, log IGC50(-1), with a short-term static protocol in the Tetrahymena population growth inhibition bioassay. Quantitative structure-activity relationships (QSAR) were examined using the 1-octanol/water partition coefficient (log K(ow))(More)
We introduce an interferometric method for measuring the profiles of cylindrical surfaces. A Fizeau interferometer with a flat reference is used to test part of a cylindrical surface, and various parts of the surface can be tested by the rotation of the surface. The algorithm for linking separate measurements is described, and testing examples for measuring(More)
The relative toxicity of selected aryl and/or alkyl alcohols was evaluated in the batch culture Tetrahymena pyriformis population-growth impairment assay. Chemicals evaluated included normal and branched primary alcohols with mono-, bi- or diaromatic substituents as well as aryl-substituted ethers. Log 1-octanol/water partition coefficients (log Kow) along(More)