Duncan Macrae

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BACKGROUND Meningococcal disease is still associated with considerable mortality, despite the use of early antibiotics and management in specialised intensive care units, due principally to early refractory myocardial depression and hypotension as well as severe acute respiratory distress syndrome. Extracorporeal membrane oxygenation (ECMO) is a complex(More)
We obtained audiograms and auditory brainstem responses from 44 patients with Duane's retraction syndrome to assess the incidence and nature of hearing deficit. Of 44 patients, seven (15.9%) had evidence of hearing impairment. Three (6.8%) subjects had a temporary conductive hearing loss because of middle ear fluid, and another patient had hearing loss from(More)
Intracranial pressure and brain compliance in traumatic brain injury Elevated intracranial pressure (ICP) has been associated with increased mortality in patients with severe traumatic brain injury (TBI). More than 20 years ago, Marmarou [1], while analysing the data from the traumatic coma data bank (TCDB), recognized that the proportion of hourly ICP(More)
Cardiovascular Cardiac failure: epidemiology and treatment Mebazaa and colleagues in two interesting papers [1, 2] described the clinical presentation, management, and outcomes of acute heart failure (AHF) through the Acute Heart Failure Global Survey of Standard Treatment (ALARM-HF) on AHF conducted in nine countries in four continents. In the first paper(More)
BACKGROUND There is increasing evidence that tight blood glucose (BG) control improves outcomes in critically ill adults. Children show similar hyperglycaemic responses to surgery or critical illness. However it is not known whether tight control will benefit children given maturational differences and different disease spectrum. METHODS/DESIGN The study(More)
In 2012, the journal published several articles dealing with the use of noninvasive ventilation (NIV) in patients with acute respiratory failure (ARF). Carrillo et al. [1] prospectively evaluated the characteristics and outcomes of 184 patients with severe ARF due to community-acquired pneumonia treated with NIV, and determined the