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OBJECTIVE Somatostatin and its analogs have recently been introduced in the treatment of chylous effusions in infants and children following surgery. The safety profile of this treatment in critically ill patients has not been fully evaluated. DESIGN Retrospective case review. SETTING Tertiary pediatric cardiac center. PATIENTS A male infant born by(More)
Inhaled nitric oxide (iNO) was first used in neonatal practice in 1992 and has subsequently been used extensively in the management of neonates and children with cardiorespiratory failure. This paper assesses evidence for the use of iNO in this population as presented to a consensus meeting jointly organised by the European Society of Paediatric and(More)
In 2012, the journal published several articles dealing with the use of noninvasive ventilation (NIV) in patients with acute respiratory failure (ARF). Carrillo et al. [1] prospectively evaluated the characteristics and outcomes of 184 patients with severe ARF due to community-acquired pneumonia treated with NIV, and determined the
BACKGROUND Meningococcal disease is still associated with considerable mortality, despite the use of early antibiotics and management in specialised intensive care units, due principally to early refractory myocardial depression and hypotension as well as severe acute respiratory distress syndrome. Extracorporeal membrane oxygenation (ECMO) is a complex(More)
In six patients with septic shock apparent liver blood flow was significantly reduced compared with two patients restudied on recovery from shock and a group of four matched unshocked patients undergoing intensive care (287 +/- 23 ml/min vs 870 +/- 164 ml/min; mean +/- SEM). In the shocked patients the elimination half-life of morphine was significantly(More)