Dumitru Chesov

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BACKGROUND To evaluate interleukin (IL)-2 and interferon (IFN)-γ secreting T-cells in parallel for the differentiation of latent infection with Mycobacterium tuberculosis infection (LTBI) from active tuberculosis. METHODS Following ex-vivo stimulation of peripheral blood mononuclear cells (PBMC) with M. tuberculosis-specific antigens early secretory(More)
Nosocomial transmission of multidrug-resistant tuberculosis (MDR-TB) was ascertained by 24-locus mycobacterial interspersed repetitive units-variable number of tandem repeats (MIRU-VNTR) and spoligotyping at four hospitals in the Republic of Moldova, a high MDR-TB burden country. Overall, 5.1% of patients with pan-susceptible TB at baseline were identified(More)
BACKGROUND Globally there is a burgeoning epidemic of drug monoresistant tuberculosis (TB), multidrug-resistant TB (MDR-TB) and extensively drug-resistant TB (XDR-TB). Almost 20% of all TB strains worldwide are resistant to at least one major TB drug, including isoniazid. In several parts of the world there is an increasing incidence of MDR-TB, and(More)
AIM To compare the efficiency of some prognostic scores in patients with severe influenza pneumonias. MATERIALS AND METHODS The study was performed on a cohort of 75 cases of 2009 AH1N1 influenza associated pneumonias. Clinical and laboratory features at admission were used to calculate retrospectively the following prognostic scores: SCAP (Severe(More)
2 mm thickness [1] . It is a relatively specific sign for cryptogenic organizing pneumonia [1, 2] , but the differential diagnosis list should also include: bacterial pneumonia, lymphomatoid granulomatosis, Wegener’s granulomatosis, tuberculosis, mucormycosis, paracoccidioidomycosis, sarcoidosis, cancer and pulmonary infarction. Although the pathogenesis of(More)
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