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OBJECTIVE To evaluate the clinicopathologic characteristics and prognostic factors of ovarian granulosa cell tumors. METHODS Medical records of 113 patients presenting between January 1995 and December 2007 were retrospectively reviewed. RESULTS One-hundred two patients had adult type disease, with a mean age of 46.2 years (range, 18 to 83 years) and a(More)
OBJECTIVE The purpose of this study is to elucidate the usefulness of magnetic resonance imaging (MRI) and positron emission tomography (PET) for the detection of parametrial involvement and lymph node metastasis in patients with cervical cancer. METHODS Thirty-six patients with cervical cancer were retrospectively enrolled. MRI and PET scans were(More)
Osteoradionecrosis (ORN) of the pelvic bone presenting as a progressive osteolytic lesion, following three-dimensional conformal radiotherapy (3DCRT) with concurrent chemotherapy, is a clinical diagnostic challenge that must be differentiated from an osseous metastasis. We report on a case with an unusual presentation of ORN mimicking bony metastasis that(More)
PURPOSE To investigate the incidence, clinical characteristics, and risk factors of pelvic insufficiency fracture (PIF) after pelvic radiotherapy (RT) in cervical cancer. METHODS AND MATERIALS Medical records and imaging studies, including bone scintigraphy, CT, and MRI of 557 patients with cervical cancer who received whole-pelvic RT between January 1998(More)
To understand the molecular mechanisms by which anti-p185 antibody and the ligand heregulin inhibit tumor growth, we have investigated several signaling proteins and pathways. We report here that anti-p185 monoclonal antibody ID5 induced tyrosine phosphorylation of HER2 in SKBr3 breast cancer cells that overexpress p185. Heregulin b1 induced phosphorylation(More)
Purpose : This study was undertaken to evaluate the optimal exposure time for nuclear envelope breakdown (NEBD) after injection of a round spermatid and to investigate the effect of oocyte activation timing on the fertilization rate and early embryo development in porcine round spermatid injection procedure. Methods : Injected oocytes were fixed at 0.5, 1,(More)
OBJECTIVES To evaluate the effect of rec-FSH on the ovarian follicular environment in controlled ovarian hyperstimulation (COH) cycle, we compared the expression of the markers that have been reported to reflect the follicle health. STUDY DESIGN A total of 31 women (<35 years) with normal ovarian function were allocated to three different COH protocols(More)
OBJECTIVE The purpose of this study was to determine the prognostic significance of tumor volume regression rate during radiotherapy (RT) measured by three serial magnetic resonance imaging (MRIs) studies performed in patients treated with RT alone and compare the results with patients treated with concurrent chemoradiotherapy (CCRT). METHODS We evaluated(More)
BACKGROUND Magnetic resonance imaging (MRI) has been frequently used to determine a preoperative treatment plan for gynecologic cancers. However, the MR accuracy for staging an endometrial cancer is not satisfactory based on the old FIGO staging system. PURPOSE To evaluate MR accuracy for staging endometrial cancer using the new FIGO staging system. (More)
The objectives of this study were to determine the usefulness of magnetic resonance (MR) imaging in the differentiation of various lesions causing an abnormality of the endometrial cavity by evaluating the imaging features on dynamic contrast-enhanced study and late contrast-enhanced T1-weighted images (T1WI). Contrast-enhanced MR imaging of 59(More)