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  • Peter Sazani, Kirk P. Van Ness, Doreen L. Weller, Duane Poage, Keith Nelson, And Stephen B Shrewsbury
  • Biology, Medicine
  • International journal of toxicology
  • 2011 (First Published: 1 May 2011)
  • AVI-4658 is a phosphorodiamidate morpholino oligomer (PMO) designed to induce skipping of dystrophin exon 51 and restore its expression in patients with Duchenne muscular dystrophy (DMD).Continue Reading
  • Peter Sazani, Kirk P. Van Ness, Doreen L. Weller, Duane Poage, Kiran Palyada, Stephen B. Shrewsbury
  • Chemistry, Medicine
  • International journal of toxicology
  • 2011 (First Published: 1 May 2011)
  • AVI-4658 is a phosphorodiamidate morpholino oligomer (PMO) drug designed to restore dystrophin expression in a subset of patients with Duchenne muscular dystrophy (DMD). Previous reports demonstratedContinue Reading
  • Ronnie L Yeager, Dong Zhao, Yan hua Lan, Duane Poage, C Thomas Lin, Michael D. Duvall
  • Medicine
  • Regulatory toxicology and pharmacology : RTP
  • 2011 (First Published: 1 June 2011)
  • Cynomolgus monkeys are an important and widely used species in preclinical toxicology studies. During the in-life phase of study, body weight effects may be indicative of toxicity; however, trends inContinue Reading