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Spectral components of heart rate variability (HRV) are determined in the time-frequency domain using a wavelet transform. Based on the finer estimation of low-frequency content enabled by the logarithmic resolution of the wavelet transform, corrections of spectral intervals, already defined by Fourier and model based methods, are proposed. The(More)
MicroRNAs are non-coding RNAs, functionioning as post-transcriptional regulators of gene expression. Some microRNAs have been demonstrated to play a role in regulation of innate immunity. After myocardial infarction (MI), innate immunity is activated leading to an acute inflammatory reaction. There is evidence that an intense inflammatory reaction might(More)
Cyclooxygenase (COX) is a key enzyme in prostanoid synthesis. It exists in two isoforms, COX-1 and COX-2. COX-1 is referred to as a 'constitutive isoform', and is considered to be expressed in most tissues under basal conditions. In contrast, COX-2 is referred to as an 'inducible isoform', which is believed to be undetectable in most normal tissues, but can(More)
A significant proportion of patients with ventricular fibrillation (VF) can only be defibrillated after a period of chest compressions and ventilation before the defibrillation attempt. In these patients, unsuccessful defibrillations increase the duration of heart arrest and reduce the possibility of a successful resuscitation, which could be avoided if a(More)
Our aims were to determine whether mild therapeutic hypothermia (MTH) is associated with ECG changes similar to those observed in accidental hypothermia, and to use advanced ECG parameters to further characterize any electrophysiological changes associated with MTH. The study included 46 patients (35 after primary, 9 after secondary, and 2 after heart(More)
Our aim was to evaluate electrocardiographic (ECG) diferences between survivors and non-survivors of out of hospital cardiac arrest (OHCA). The study included 76 patients that suffered from OHCA. In all patients, serum arterial lactate was obtained on admission to the intensive care unit was obtained as an index of ischemia during cardiac arrest and(More)
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