Drew H. Barzman

Learn More
OBJECTIVE To determine the comparative efficacy of quetiapine and divalproex for the treatment of adolescent mania. METHOD Fifty adolescents (ages 12-18 years) with bipolar I disorder, manic or mixed episode, were randomized to quetiapine (400-600 mg/day) or divalproex (serum level 80-120 microg/mL) for 28 days for this double-blind study, which was(More)
OBJECTIVE The aim of this study was to compare the efficacy and tolerability of quetiapine and divalproex for the treatment of impulsivity and reactive aggression in adolescents with co-occurring bipolar disorder and disruptive behavior disorders. METHOD Patients were included in this post hoc analysis if they scored > or = 14 on the Positive and Negative(More)
Insight on the part of both patients and their significant others is thought to be an important factor influencing compliance with medication and treatment of schizophrenic patients. Using the Scale to Assess Unawareness of Mental Disorder, the insight and the awareness of patients and of their significant others were studied with respect to symptoms,(More)
OBJECTIVE The purpose of this study was to examine body mass indexes (BMI) and lipid profiles of children and adolescents hospitalized for a psychiatric illness and exposed to an atypical antipsychotic. METHOD Medical records of children and adolescents (ages of 5-18 years) with an inpatient psychiatric hospitalization between July 1, 2004, and June 30,(More)
OBJECTIVE The aim of this study was to assess topiramate as adjunctive treatment in children and adolescents hospitalized with bipolar disorders. METHODS Medical records of all children and adolescents with a Diagnostic and Statistical Manual of Mental Disorders, 4th edition (DSM-IV-TR) (APA, 2000) diagnosis of bipolar disorder, type I, hospitalized for(More)
OBJECTIVE The aim of this retrospective chart review was to evaluate the effectiveness and tolerability of aripiprazole for the treatment of children and adolescents with bipolar disorders. METHODS The medical charts of all children and adolescents with a DSM-IV diagnosis of bipolar disorder, type I, type II, not otherwise specified (NOS), or(More)
OBJECTIVE Depressive and anxiety disorders are common in youth who are at risk for bipolar disorder (i.e., youth who have at least one parent with bipolar disorder) and antidepressants are commonly prescribed as treatment. However, there are few data regarding the safety and tolerability of antidepressants in this population. Therefore, we sought to(More)
OBJECTIVE Our primary objective was to evaluate the effectiveness and tolerability of intramuscular ziprasidone for impulsivity and agitation in psychiatrically hospitalized children and adolescents. Our secondary objective was to examine demographic and clinical factors associated with treatment response. METHOD We conducted a retrospective chart review(More)
Aggression is a common management problem for child psychiatry hospital units. We describe an exploratory study with the primary objective of establishing the feasibility of linking salivary concentrations of three hormones (testosterone, dehydroepiandrosterone [DHEA], and cortisol) with aggression. Between May 2011 and November 2011, we recruited 17(More)
The Brief Rating of Aggression by Children and Adolescents (BRACHA) is a 14-item instrument scored by emergency room staff members to assess aggression risk during an upcoming psychiatric hospitalization. In this study, we investigated the inter-rater reliability of the BRACHA 0.9, the latest version of the instrument. After receiving training based on the(More)