Drahomíra Faktorová

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Distribution and Phylogeny of EFL and EF-1α in Euglenozoa Suggest Ancestral Co-Occurrence Followed by Differential Loss

Gillian H Gile, Drahomíra Faktorová, +5 authors Patrick J Keeling
PloS one
2009

BACKGROUND The eukaryotic elongation factor EF-1alpha (also known as EF1A) catalyzes aminoacyl-tRNA binding by the ribosome during translation. Homologs of this essential protein occur in all domains… (More)

Architecture of the trypanosome RNA editing accessory complex, MRB1

Michelle L. Ammerman, Kurtis M. Downey, +7 authors Laurie K. Read
Nucleic acids research
2012

Trypanosoma brucei undergoes an essential process of mitochondrial uridine insertion and deletion RNA editing catalyzed by a 20S editosome. The multiprotein mitochondrial RNA-binding complex 1 (MRB1)… (More)

Unusual mitochondrial genome structures throughout the Euglenozoa.

Joannie Roy, Drahomíra Faktorová, Julius Lukeš, Gertraud Burger
Protist
2007

Mitochondrial DNA of Kinetoplastea is composed of different chromosomes, the maxicircle (bearing 'regular' genes) and numerous minicircles (specifying guide RNAs involved in RNA editing). In… (More)

Functional characterization of two paralogs that are novel RNA binding proteins influencing mitochondrial transcripts of Trypanosoma brucei.

Lucie Kafková, Michelle L. Ammerman, +6 authors Hassan Hashimi
RNA
2012

A majority of Trypanosoma brucei proteins have unknown functions, a consequence of its independent evolutionary history within the order Kinetoplastida that allowed for the emergence of several… (More)

T7 polymerase-driven transcription is downregulated in metacyclic promastigotes and amastigotes of Leishmania mexicana.

Aygul Ishemgulova, Natalya I. Kraeva, Drahomíra Faktorová, Lucie Podešvová, Julius Lukeš, Vyacheslav Yurchenko
Folia parasitologica
2016

In our previous work we established a T7 polymerase-driven Tetracycline-inducible protein expression system in Leishmania mexicana (Biagi, 1953). We used this system to analyse gene expression… (More)

Description of Rhynchopus euleeides n. sp. (Diplonemea), a free-living marine euglenozoan.

Joannie Roy, Drahomíra Faktorová, Oldřich Benada, Julius Lukeš, Gertraud Burger
The Journal of eukaryotic microbiology
2007

We describe Rhynchopus euleeides n. sp., using light and electron microscopy. This free-living flagellate, which was isolated earlier from a marine habitat, can be grown axenically in a rich medium… (More)

Trypanosoma brucei binding proteins influencing mitochondrial transcripts of Functional characterization of two paralogs that are novel RNA Material

Lucie Kafková, Michelle L. Ammerman, +6 authors Hassan Hashimi
2012

Post-transcriptional mending of gene sequences: Looking under the hood of mitochondrial gene expression in diplonemids.

Matus Valach, Sandrine Moreira, Drahomíra Faktorová, Julius Lukeš, Gertraud Burger
RNA biology
2016

The instructions to make proteins and structural RNAs are laid down in gene sequences. Yet, in certain instances, these primary instructions need to be modified considerably during gene expression,… (More)

Transformation of Diplonema papillatum, the type species of the highly diverse and abundant marine microeukaryotes Diplonemida (Euglenozoa).

Binnypreet Kaur, Matus Valach, +5 authors Drahomíra Faktorová
Environmental microbiology
2018

Diplonema papillatum is the type species of diplonemids, which are among the most abundant and diverse heterotrophic microeukaryotes in the world's oceans. Diplonemids are also known for a unique… (More)

Integrity of the core mitochondrial RNA-binding complex 1 is vital for trypanosome RNA editing.

Zhenqiu Huang, Drahomíra Faktorová, +4 authors Hassan Hashimi
RNA
2015

Trypanosoma brucei is the causative agent of the human and veterinarian diseases African sleeping sickness and nagana. A majority of its mitochondrial-encoded transcripts undergo RNA editing, an… (More)

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