Dragoș Florea

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AIM The study aimed to evaluate the clinical utility of the chemiluminescent HCV core Ag test compared to viral load assessment in the management of patients with chronic hepatitis C. METHODS A retrospective study was performed at a tertiary-care infectious diseases hospital on samples collected from anti-HCV positive patients. Seventy-six samples were(More)
OBJECTIVES We analysed the distribution of vaccine and non-vaccine Streptococcus pneumoniae serotypes and the antimicrobial susceptibility of pneumococcal strains isolated from healthy Romanian children. METHODS A multi-centre cross-sectional study was performed in four counties to evaluate carried strains of S. pneumoniae isolated from 2000 children aged(More)
Liver abscess was diagnosed in a man presenting with fever, chills and severe myopathy. The K. pneumoniae isolated from blood cultures belonged to the K1 serotype. The patient responded favourably to percutaneous drainage of the abscess and antibiotics. This is the first documented report of Klebsiella pneumoniae liver abscess syndrome (KLAS) described in(More)
BACKGROUND The need to limit the spread of drug-resistant Mycobacterium tuberculosis requires rapid detection of resistant strains. The present study aimed to evaluate a commercial assay using broad-range PCR coupled with electrospray ionization mass spectrometry (PCR/ESI-MS) for the rapid detection of isoniazid (INH) and rifampin (RIF) resistance in M.(More)
Objective: to estimate the rate and the significance of low level viraemia in HIV positive patients registered in the National Institute for Infectious Diseases " Prof. Dr. Matei Balş " , Bucharest, Romania. We retrospectively analysed the rate of HIV viral loads (VL) <200 copies/mL in patients admitted in our institute from 2011 to 2013. The patients with(More)
Background With the advent of direct-acting antivirals, the rate of sustained virologic response (SVR) after treatment for chronic HCV infection has dramatically increased [1]. However, recent data show that there is cause for concern regarding the potential emergence of viral resistance [2]. Methods We performed a study to assess the antiviral resistance(More)