Dragoș Florea

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OBJECTIVES We analysed the distribution of vaccine and non-vaccine Streptococcus pneumoniae serotypes and the antimicrobial susceptibility of pneumococcal strains isolated from healthy Romanian children. METHODS A multi-centre cross-sectional study was performed in four counties to evaluate carried strains of S. pneumoniae isolated from 2000 children aged(More)
Despite the major medical advance, over 350 million people worldwide still have chronic infection with hepatitis B virus and HBV-associated liver disease remains a major cause of morbidity and mortality. 15-50% of patient VHB infected have serological markers for VHD co-infection. We retrospectively studied 252 cases of acute hepatitis B (AHB) admitted in(More)
BACKGROUND The need to limit the spread of drug-resistant Mycobacterium tuberculosis requires rapid detection of resistant strains. The present study aimed to evaluate a commercial assay using broad-range PCR coupled with electrospray ionization mass spectrometry (PCR/ESI-MS) for the rapid detection of isoniazid (INH) and rifampin (RIF) resistance in M.(More)
Objective: to estimate the rate and the significance of low level viraemia in HIV positive patients registered in the National Institute for Infectious Diseases " Prof. Dr. Matei Balş " , Bucharest, Romania. We retrospectively analysed the rate of HIV viral loads (VL) <200 copies/mL in patients admitted in our institute from 2011 to 2013. The patients with(More)
Background With the advent of direct-acting antivirals, the rate of sustained virologic response (SVR) after treatment for chronic HCV infection has dramatically increased [1]. However, recent data show that there is cause for concern regarding the potential emergence of viral resistance [2]. Methods We performed a study to assess the antiviral resistance(More)