Dr. rer. nat. Olaf Gefeller

Learn More
PURPOSE The effect of the sensitizer razoxane on soft tissue sarcomas (STS) was prospectively evaluated in a randomized, controlled trial. The main purpose of the study was to determine the response rates and local control under the combined treatment compared to irradiation alone. METHODS AND MATERIALS Between 1978 and 1988, 144 patients entered the(More)
A review of the literature shows minimal success in relation to the treatment of hepato-blastoma. Recent improvements have been related to better techniques of liver resection. No final therapeutic recommendations can be made but prophylactic chemotherapy is indicated. The authors present a surprisingly successful patient who had a non-resectable(More)
Between 1981 and 1985, 290 patients with malignant sof t t issue tumors were registered in the CWS-81 study. These patients came from 48 c l in ics in West Germany, 185 of them (63.8%) were rhabdomyosareomas (RMS). The disease-free survival rate (DSF) fo r stage I is 83%, fo r stage I I 64%, fo r stage I I I 52%, fo r stage IV 33% and for stages I I V 57%.(More)
Die Problematik der Verallgemeinerung von Ergebnissen einer epidemiologischen Studie auf Populationen jenseits der Studienpopulation wird seit langem kontrovers in der epidemiologischen Literatur diskutiert. Für diesen Schluss auf weitere Populationen gibt es aus methodischer Sicht keine Rechtfertigung mehr, er stellt einen inhaltlich zu begründenden(More)
UNLABELLED Since January 1982, we have treated in a phase-II study 28 patients with a low-dose cis-platinum therapy combined with radiotherapy. We wanted to study the effect of reduced doses of cis-diamino-dichloroplatinum (II) in three different dose patterns: 1. "higher" dosage (150 mg/m2 within six weeks), single dose: 25 mg/m2 one time per treatment(More)
During 1973–1980, 19 children were treated with rhabdomyosarcoma of various localizations with the result that 10 patients are disease-free (follow-up of 8 months to 7 years). The treatment of the 9 deceased patients will be discussed. We conclude that the primary treatment should be a radical operation only in completely resectable tumors. If primary(More)
From 1971 to 1980, 639 patients with carcinoma of the cervix and 271 patients with endometrial cancer were treated in the Division of Radiation Therapy of the Medical School Hannover. In 606 patients radical radiation therapy was followed by routine surgery, 304 patients have been irradiated primarily due to the local spread of the tumor. The radiation(More)
  • 1