Dr. med. Paul Sokolow

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Phosphorus nuclear magnetic resonance (31P NMR) spectroscopy is a non-destructive analytical laboratory technique that, due to recent technical advances, has become applicable to the study of high-energy phosphate metabolism in both animal and human extremity muscles (in vivo). 31P NMR can assay cellular phosphocreatine, ATP, inorganic phosphate, the(More)
Transient peaks or "spikes" frequently appear in the initial segments of torque curves recorded with the Cybex isokinetic dynamometer. The purpose of this investigation was to determine whether these spikes represent artifact or transient initial surges of true muscular force output. Cinematographic analysis using both inert weights and a human subject as(More)
Despite numerous studies investigating the pathophysiology of tourniquet ischemia, definitive data at the cellular level have been lacking and no consensus regarding safe tourniquet-application times in extremity surgery has emerged. In light of the particular vulnerability of skeletal muscle to ischemic injury, we determined the degree of muscular(More)
Of all tissues of the extremities, muscle is the least tolerant of ischemia. Hypothermia of tissue is considered beneficial for the maintenance of viability of muscle in amputated limbs before surgical replantation, but it has never been established that conventional cooling in an ice bath or its equivalent (temperature of tissue, approximately 1 degree(More)
31P NMR is used to determine the relationship between work output in the exercising human forearm and the steady-state capability of oxidative phosphorylation as measured by the phosphocreatine/inorganic phosphate ratio (PCr/Pi). Exercise intensities (one contraction per 5 sec) permitting comfortable continuation of activity for greater than 1 hr produced(More)
UNLABELLED Following traumatic limb amputation it is common clinical practice to maintain the ischemic tissues in a hypothermic state until surgical reimplantation. Of all extremity tissues, muscle is the most sensitive to ischemia; it is therefore imperative that reperfusion be established before diffuse muscle necrosis. Although it has been shown both(More)
Es ist bekannt, dass bei Erkrankungen eines zentralen Sinnesapparates entsprechende Halluzinationen sich zuweilen einstellen. So sind Gesichtshalluzinationen bei Erkrankungen des Hinterhauptslappens~ GehSrshalluzinationen bei Erkrankungen des Schllifenlappens mitgeteilt worden. In analoger Weise sind Halluzinationen bei Erkrankungen der peripheren(More)
In meiner friiheren Arbeit fiber ,Die experimentelle Ausl6sung der GehSrshalluzinationen durch periphere Reize "1) bin ich zu dem Ergebnis gekommen, dass 1. die GehSrshalluzinationen dutch akustische und auch andere Reize experimentell ausgelSst werden kSnnen~ wobei die ersteren zur Ausliisung dieser HaIluzinationen mehr geeignet sind; 2. zwisehen der(More)
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