Dr Thomas C. Chalmers

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T-cells specific for a region of human myelin basic protein, amino acids 87-99 (hMBP87-99), have been implicated in the development of multiple sclerosis (MS) a demyelinating disease of the central nervous system. Administration of soluble altered peptide ligand (APL), made by substituting native residues with alanine at either positions 91(91K > A or A91)(More)
In 1979, Wertheimer and Leeper reported an increased risk of cancer mortality among children living near ‘electrical wiring configurations’, suggestive of high current flow. Since then, numerous, often inconclusively small, investigations with conflicting results have studied the possible asociation between exposure to electric and magnetic fields (EMF) and(More)
Insulin-like growth factors I and II (IGF-I and IGF-II) play an important role in normal growth and brain development and protect brain cells from several forms of injury. The effects of IGFs are mediated by type-I and type-II receptors and modulated by potentially six specific binding proteins that form high-affinity complexes with IGFs in blood and(More)
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