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Urinary tract infections are the most common bacterial infections affecting millions of people each year worldwide. The animal model provides an excellent and suitable system for studying cystitis and pyelonephritis caused by Escherichia coli and other uropathogens. Using this established model, we evaluate the role of antioxidant defence system, renal(More)
Most individuals who develop cardiovascular disease (CVD) have cluster of multiple risk factors like dyslipidaemia, hypertension and hyperglycaemia. This cluster have termed as metabolic syndrome. It is well known that the prevalence of obesity, diabetes and metabolic syndrome all increase with age and linking to oxidative stress markers. Very few studies(More)
We evaluate the role of antioxidant enzyme status and inflammatory cascade in disease progression of cystitis in a rat model. The animals were injected with clinically isolated Uropathogenic Escherichia coli (UPEC) and study the effect of various antioxidant enzymes and inflammatory markers in disease pathology on the 0th day, 12 h and 7th day of infection.(More)
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