Dr Stefano Centanni

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Metabolism of arachidonic acid via the 5-lipoxygenase (5-LO) pathway leads to the formation of hydroperoxyeicosatetraenoic acids (HPETEs) and leukotriene (LT) A4. This unstable allylic epoxide can be further converted by secondary enzymes into LTB4 and cysteinyl LTs. LTs represent a family of potent biologically active compounds synthesised by specific cell(More)
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