Dr. Ralph Wright D. PHIL

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Latent inhibition (LI) refers to retarded conditioning to a stimulus as a consequence of its nonreinforced preexposure. LI is impaired in acute schizophrenic patients and in rats treated with amphetamine. Neuroleptic drugs enhance LI, and this effect is selective and specific for this class of drugs. The present experiments tested the proposition that(More)
Image signal-to-noise ratio and power dissipation are investigated theoretically up to 400 MHz. While the text is mathematical, the figures give insights into predictions. Hertz potential is introduced for probe modeling where charge separation cannot be ignored. Using a spherical geometry, the potential from current loops that would produce a homogeneous(More)
The specter of antibiotic-resistant bacteria has provoked renewed interest in the possible use of bacteriophages to control bacterial infections. We argue that clinical application of phage therapy has been held back by a failure to appreciate the extent to which the pharmacokinetics of self-replicating agents differ from those of normal drugs. For(More)
Previous research has suggested that links between autonomic nervous system functioning and violence are strongest in those who come from benign home backgrounds, but there appears to be no similar research using brain-imaging measures of central nervous system functioning. It was hypothesized that murderers who had no early psychosocial deprivation (e.g.,(More)
Alzheimer's disease (AD) affects a large proportion of the increasingly aging population of this country, with prevalence rates as high as 47% for those >85 years old and a total annual cost approaching $70 billion. There is no currently validated test for detection of dementia of the Alzheimer type (DAT). Because of this and the insidious onset of the(More)
The CardioVascular Research Grid (CVRG) Project’s goal is to facilitate research on heart disease through open-source informatics and data analysis tools, making it easier for researchers to manage, share, and analyze complex data collected in cardiovascular studies. Inefficient mechanisms for sharing and analyzing data hamper large studies and make it hard(More)
The role of the splanchnic circulation in normal subjects during sympathoneural activation induced by stimuli which either raise (mental arithmetic, cold pressor test, isometric exercise) or maintain (head-up tilt) blood pressure has been studied by measuring superior mesenteric artery blood flow using a noninvasive Doppler ultrasound method in 18 normal(More)