Dr. Johnson L. Thistle

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A dose-response study comparing ursodeoxycholic and chenodeoxycholic acid was carried out in six men with asymptomatic radiolucent gallstones present in well-visualizing gallbladders. The study tested the effects of a low (averaging 6 mg/kg/day) or medium dose (averaging 11 mg/kg/day) of each bile acid on the cholesterol saturation of bile as well as on(More)
Who needs urso? Perhaps it is your patient who has radiolucent gallstones but a substantially increased risk for surgery. However, if urso (ursodiol) works no better than cheno (chenodiol) (and that remains to be established), is it likely to have much utility in clinical practice? Turning first to cheno, some have interpreted the complete stone dissolution(More)
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