Dr. John G. Moore

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This paper presents an innovative sensor system, created specifically for new civil engineering structural monitoring applications, allowing specially packaged fiber grating-based sensors to be used in harsh, in-the-field measurement conditions for accurate strain measurement with full temperature compensation. The sensor consists of two fiber Bragg(More)
Radiolabeled liquid and solid portions of standardized 300-g meals were administered on four different study days to eight healthy subjects in an attempt to define the range of inter- and intrasubject variability in gastric emptying. Meal half emptying times, analysis of variance, and intraclass correlations were computed and compared within and between(More)
A model for gastric mucosal injury is proposed in which a key pathogenetic event is the disruption in the normal relationships among several circadian rhythms of gastric function. In the rat a circadian rhythm in acid secretion was found to be out of phase with a circadian rhythm in gastric pepsin secretion, another aggressive factor, and several mucosal(More)
The gastric emptying rates of combined liquid and solid radioisotopically labeled meals in 47 healed duodenal ulcer subjects and 17 healthy control subjects are compared. No significant differences were found between the groups in emptying slopes and the emptying half-times or in the percent retention values at any of the counting intervals for either the(More)
Gastric acid secretion was stimulated by the preparation and anticipation of a self-selected meal in five healthy male subjects. The purpose of the investigation was to determine whether intravenous (IV) or intraduodenally (ID) administered glucose solution given during the test hour of meal preparation and anticipation altered psychically stimulated acid(More)
A dual radioisotopic method was employed to study the rate of gastric emptying of meals in ten males with an average age of 31 years and 10 elderly males with an average age ot 76.4 years. All study subjects were fed a standardized 900-g meal labeled with a liquid (111indium-DTPA) and solid (99mtechnetium-tagged liver) phase isotopic marker. There were no(More)
Forty-five subjects with healed duodenal ulcer were administered either a placebo or a low-dose or high-dose regimen of misoprostol, a synthetic PGE1 analog, in a doubleblind, random, parallel-group design to assess the effect of this prostaglandin compound on the gastric emptying of liquid-solid meals. A dual-radionuclide technique to measure liquid-and(More)
Twenty-four-hour basal acid collections and 4-hour insulin-stimulated gastric secretory tests were obtained in 21 male patients who had vagotomy and pyloroplasty for duodenal ulcer disease from 2 to 11 years previously. Eleven demonstrated high basal acid secretory rates. All members of this group had “inadequate vagotomies” by most criteria which are based(More)
This study was designed to assess the relative influence of meal weight and caloric content on gastric emptying of liquid and solid meals in man. A dual radioisotopic method which permits noninvasive and simultaneous measurement of liquid-and solid-phase emptying by external gamma camera techniques was employed. Nine healthy volunteer subjects ingested(More)
Modern and ancient human feces (coprolites) and modern nonhuman animal fecal samples were subjected to headspace gas-chromatographic analysis for detection of odors related to dietary intake. The odors of grass, green leaves, licorice, meat, and corn were detected in coprolites dating to 6400 years BP (before present). Analysis of modern human samples(More)