Dr. Herbert Sprince Chief of Research Biochemistry

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Intraperitoneal injection into rats of 5.5 mM/kg ofdl-homocysteine (free base) ordl-homocysteine thiolactone · HCl resulted in violent convulsions (approx. 50%) and some fatalities (approx. 15%), following a short, initial period of depressant activity. Metabolically related metabolites (viz. methionine, serine, homoserine, cysteine and homocystine) showed(More)
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