Dr. D. Baller

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According to Hagen-Poiseuille' s law coronary vascular resistance depends on viscosity of blood and the fourth power of vascular radius. In vitro investigations have shown increasing of whole blood viscosity after mixing with contrast media caused by shrinking of erythrocytes due to hyperosmolality of contrast media compared to blood. However, because of(More)
Since the cardiac efficiency is, by definition, the ratio between left ventricular stroke work and energy demand, changes in hemodynamics influence cardiac work and energy demand competitively. An increase in hemodynamics results in an increase in the cardiac work which would give a better cardiac efficiency but on the other hand, also increases the energy(More)
By use of argon and helium instead of N20 in the inert gas method for determination of tissue blood flow a marked shortening of the equilibrium period was achieved. However, the presently used gaschromatographic detection technique is applicable only to single samples analysis and does not yield sufficiently detailed information on the indicator mash-in(More)
The effects of ventricular pacing (90–330 beats/min) and atrial pacing (120–210 beats/min) on myocardial oxygen consumption $$(M\dot VO_2 )$$ and its hemodynamic determinants and on myocardial pumping efficiency were studied systematically on intact dogs. In six closed-chest experiments 158 steady states were analyzed. Myocardial blood flow was measured(More)
To investigate the basis of cardiodepressive side effects in coronary arteriography, the isolated effects of different contrast media on electrolyte levels in blood (and blood fractions) were quantified in vitro. Due to their sodium content and calcium chelation, ionic media cause an imbalance in the extracellular Na+/Ca++-ratio that determines myocardial(More)
A marked increase in left ventricular diastolic pressure $$(\bar P_{LVD} )$$ relative to volume is regularly observed during angina pectoris and may contribute to further deteriorations of myocardial perfusion in the ischemic myocardium and to pulmonary congestion as well. A possible simultaneous increase in myocardial oxygen consumption (MVO2) due to a(More)
The measurement accuracy of clinically applicable methods for blood flow measurement in coronary sinus — continuous local thermodilution (LTD), differential pressure (DP), ultrasonic Doppler (US) and the electromagnetic flow measurement method (EMF) — was examined in 15 anaesthetized closed chest dogs with left ventricle weights between 150 and 200 g. The(More)
Myocardial oxygen consumption indices that are frequently applied to man such as tension-time index (TTI), pressure-rate product (P·HR) and triple product (TP) have not been fully validated so far. These easily obtainable indices and a modified TTI $$(\overline P \cdot \sqrt {HR} )$$ , therefore, were examined in 10 closed-chest dogs with very broad(More)
Since the cardiac efficiency is, by definition, the ratio between left ventricular stroke work and energy demand, changes in hemodynamics influence cardiac work and energy demand competitively. An increase in hemodynamics results in an increase in the cardiac work which would give a better cardiac efficiency but on the other hand, also increases the energy(More)
In 9 open-chest mongrel dogs 4–6 intermittent 3-min occlusions of the LAD artery were performed with time intervals of about 45 min. Using a μ-computer, the following variables, were calculated online: energy demand according to the Bretschneider equation (Et) from digitized hemodynamic data; myocardial oxygen consumption (M $$\dot V$$ O2) from(More)