Dr Cliff Mann

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OBJECTIVES To establish the safety of an intranasal diamorphine (IND) spray in children. DESIGN An open-label, single-dose pharmacovigilance trial. SETTING Emergency departments in eight UK hospitals. PARTICIPANTS Children aged 2-16 years with a fracture or other trauma. OUTCOME MEASURES Adverse events (AE) specifically related to nasal irritation,(More)
Endocrine excesses or deficiencies frequently result in alterations of height as compared with age-matched children. Less clinically obvious are significant alterations in bone metabolism leading to osteoporosis, which can affect the child and may affect the patient as an adult. Slipped capital femoral epiphysis appears to be associated with a variety of(More)
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