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Electronic health records (EHRs) are an important source of data for detection of adverse drug reactions (ADRs). However, adverse events are frequently due not to medications but to the patients' underlying conditions. Mining to detect ADRs from EHR data must account for confounders. We developed an automated method using natural-language processing (NLP)… (More)

We solve a long-standing problem—determining structural information for disordered materials from their diffraction spectra—for the special case of planar disorder in close-packed structures (CPSs). Our solution offers the most complete possible statistical description of the disorder and, from it, we find the minimum effective memory length for stacking… (More)

- Dowman P Varn, D P Iv [ † ] Varn, +35 authors Smith

This thesis represents the first formal presentation of the algorithm for-machine reconstruction from spectral data called-machine spectral reconstruction theory or MSR. As might be expected from a work that introduces a novel approach—let alone one that is written by a student to satisfy the requirements of a degree—there is significant attention given to… (More)

We analyze solid-state phase transformations that occur in zinc-sulfide crystals during annealing using a random deformation-faulting mechanism with a very simple interaction between adjacent close-packed double layers. We show that, through annealing, infinite-range structures emerge from initially short-range crystal order. That is, widely separated… (More)

- Paul M. Riechers, Dowman P. Varn, James P. Crutchfield
- ArXiv
- 2014

SFI Working Papers contain accounts of scienti5ic work of the author(s) and do not necessarily represent the views of the Santa Fe Institute. We accept papers intended for publication in peer-‐reviewed journals or proceedings volumes, but not papers that have already appeared in print. Except for papers by our external faculty, papers must be based on work… (More)

- D P Varn, G S Canright, J P Crutchfield
- Acta crystallographica. Section A, Foundations of…
- 2013

In previous publications [Varn et al. (2002). Phys. Rev. B, 66, 174110; Varn et al. (2007). Acta Cryst. B63, 169-182] we introduced and applied a new technique for discovering and describing planar disorder in close-packed structures directly from their diffraction patterns. Here, we provide the theoretical development behind those results, adapting… (More)

- Dowman P. Varn, James P. Crutchfield
- ArXiv
- 2014

We review recent progress in applying information-and computation-theoretic measures to describe material structure that transcends previous methods based on exact geometric symmetries. We discuss the necessary theoretical background for this new toolset and show how the new techniques detect and describe novel material properties. We discuss how the… (More)

- D P Varn, G S Canright, J P Crutchfield
- Acta crystallographica. Section B, Structural…
- 2007

We apply epsilon-machine spectral reconstruction theory to analyze structure and disorder in four previously published zinc sulfide diffraction spectra and contrast the results with the most common alternative theory, the fault model. In each case we find that the reconstructed epsilon-machine provides a more comprehensive and detailed understanding of the… (More)

- Paul M. Riechers, Dowman P. Varn, James P. Crutchfield
- Acta crystallographica. Section A, Foundations…
- 2015

Given a description of the stacking statistics of layered close-packed structures in the form of a hidden Markov model, analytical expressions are developed for the pairwise correlation functions between the layers. These may be calculated analytically as explicit functions of model parameters or the expressions may be used as a fast, accurate and efficient… (More)

- D P Varn, G S Canright
- Acta crystallographica. Section A, Foundations of…
- 2001

Recent work on discrete classical problems in one-dimensional statistical mechanics has shown that, given certain elementary symmetries, such problems may not have a periodic (crystalline) ground state, even in the absence of fine tuning of the couplings. Here these results are applied to several families of well known polytypic materials. The families… (More)