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Approximately one-third of patients with an indication for HCT have a human leukocyte antigen (HLA) matched related donor (MRD) available to them. For the remaining patients, a matched unrelated donor (MUD) is an alternative. Prior studies comparing MRD and MUD HCT provide conflicting results, and the relative efficacy of MRD and MUD transplantation is an(More)
Parotid gland tumours account for 80% of all salivary gland neoplasms, 20% of these are malignant, but in daily clinical practice most parotid masses are operated on before obtaining the final histological diagnosis. This clinical setting further complicates the critical point of parotid surgery, which is the management of the facial nerve. In the present(More)
We examine the impact of negative clinical trial results on use of autologous hematopoietic cell transplantation (HDC/HCT) in breast cancer patients. Abandonment of occurred rapidly; one year after the results became public, volume was 20% of the 1998 peak. Teaching and research hospitals were slower to discontinue the procedure, and the pattern of decline(More)
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