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Treatment of cells with pro-inflammatory cytokines or ultraviolet radiation causes activation of the c-Jun NH2-terminal protein kinase (JNK). Activating transcription factor-2 (ATF2) was found to be a target of the JNK signal transduction pathway. ATF2 was phosphorylated by JNK on two closely spaced threonine residues within the NH2-terminal activation(More)
We present a new approach to extracting information from unstructured documents based on an application ontology that describes a domain of interest. Starting with such an ontology, we formulate rules to extract constants and context keywords from unstructured documents. For each un-structured document of interest, we extract its constants and keywords and(More)
Electronically available data on the Web is exploding at an ever increasing pace. Much of this data is unstructured, which makes searching hard and traditional database querying impossible. Many Web documents, however, contain an abundance of recognizable constants that together describe the essence of a document's content. For these kinds of data-rich,(More)
Anandamide is an endogenous ligand for delta 9-tetrahydrocannabinol (THC) receptors. Incubation of cultured cells with anandamide or THC causes increased arachidonic acid release and eicosanoid biosynthesis. Here we demonstrate that the MAP kinase signal transduction pathway contributes to this response. Treatment of WI-38 fibroblasts with anandamide causes(More)
OBJECTIVE To compare the feasibility of continuous positive airway pressure (CPAP) support generated by high flow nasal cannula with conventional CPAP for prevention of reintubation among preterm infants with a birth weight of <or=1,250 g. STUDY DESIGN Preterm infants were randomized to CPAP generated via high flow cannula or the Infant Flow Nasal CPAP(More)
This paper presents an ASOCS (Adaptive Self-Organizing Concurrent System) model for massively parallel processing of incrementally defined rule systems in such areas as adaptive logic, robotics, logical inference, and dynamic control. An ASOCS is an adaptive network composed of many simple computing elements operating asynchronously and in parallel. This(More)
This paper presents an ASOCS (adaptive self-organizing concurrent system) model for massively parallel processing of incrementally defined rule systems in such areas as adaptive logic, robotics, logical inference, and dynamic control. An ASOCS is an adaptive network composed of many simple computing elements operating asynchronously and in parallel. This(More)
The specific membrane resistivity of motoneurons at or near the soma (Rms) is much lower than the specific membrane resistivity of the dendritic tree (Rmd). The goal of the present experiments was to investigate the contribution of tonically active voltage-dependent potassium channels at or near the soma to the low Rms. These channels were blocked with the(More)