Douglas Lewis

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The PIPER (Prompting Intensity of Pain Electronic Recorder) is a compact data-logging device, easily worn by a subject. It emits audible beeps at pre-programmed times, prompting the subject to enter a pain rating by button press. Ratings are stored, for later down-loading. We report two studies suggesting that PIPER pain ratings have good reliability, and(More)
Thirty-six non-hospitalized subjects with chronic pain from OA of the knee participated in an evaluation of transcutaneous electrical nerve stimulation (TENS) and naproxen, an NSAID. All pre-experiment treatment was withdrawn. Each subject experienced in some order three 3-week treatment phases: NSAID plus placebo TENS; TENS plus placebo drug; and double(More)
BACKGROUND Fetal alcohol syndrome (FAS), alcohol-related birth defects (ARBDs), and alcohol-related neurodevelopment disorders (ARNDs) in neonates are often the result of maternal alcohol consumption during pregnancy. Facial characteristics are associated with FAS, but ARBDs and ARNDs are more difficult to diagnose. Fetal exposure to alcohol can cause(More)
Over the past decade, the use of hair specimens for the long-term detection of the alcohol biomarker ethyl glucuronide has been increasing in popularity and usage. We evaluated the usefulness of fingernail clippings as a suitable alternative to hair for ethyl glucuronide detection. A liquid chromatography-tandem mass spectrometry method for the detection of(More)
AIMS This study aimed to evaluate the performance of ethyl glucuronide (EtG) in hair and fingernails as a long-term alcohol biomarker. DESIGN Cross-sectional survey with probability sampling. SETTING Midwestern United States. PARTICIPANTS Participants were 606 undergraduate college students between the ages of 18 and 25 years at the time of selection(More)
BACKGROUND Heroin abuse is a significant public health issue and is on the rise because of the unintended consequences of strengthening controls for nonmedical use of prescription pain killers. Included in this trend is an increase in opiate exposed newborns that are particularly vulnerable to a number of negative health outcomes. METHODS After presenting(More)
We describe a clinical procedure for assessing knee pain: 10 standardised movements of the knee are made (r active and 6 passive), and the subject's behavioural response to each is scored by the assessor on a 0-3 scale. The total score is the Pain Index of the Knee (PIK). We report investigations of repeatability, inter-assessor agreement, and validity of(More)
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