Douglas J. Brown

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In this article, we seek to address a simple question: “How prevalent are denial-of-service attacks in the Internet?” Our motivation is to quantitatively understand the nature of the current threat as well as to enable longer-term analyses of trends and recurring patterns of attacks. We present a new technique, called “backscatter(More)
BACKGROUND The TARGIT-A trial compared risk-adapted radiotherapy using single-dose targeted intraoperative radiotherapy (TARGIT) versus fractionated external beam radiotherapy (EBRT) for breast cancer. We report 5-year results for local recurrence and the first analysis of overall survival. METHODS TARGIT-A was a randomised, non-inferiority trial. Women(More)
From the Department of Emergency Medicine, University of British Columbia, Vancouver (D.J.A.B.), and the Department of Emergency Medicine, Mineral Springs Hospital, Banff, AB (J.B.) — both in Canada; the Institute of Mountain Emergency Medicine, European Academy of Bolzano, Bolzano, Italy (H.B.); and the Department of Anesthesiology and Critical Care(More)
This article outlines the development of a 10-item measure of workplace ostracism. Using 6 samples (including multisource and multiwave data), the authors developed a reliable scale with a unidimensional factor structure that replicated across 4 separate samples. The scale possessed both convergent and discriminant validity, and criterion-related validity(More)
BACKGROUND AND PURPOSE Ophthalmoplegic migraine is a rare condition characterized by the association of headaches and an oculomotor nerve palsy. We report six patients with typical clinical features of this disorder in whom enhancement of the cisternal segment of the oculomotor nerve developed during the acute phase, followed by resolution of enhancement(More)
OBJECTIVE To assess the relative contribution of impaired baroreceptor reflexes and enhanced cardiovascular reactivity to the exaggerated blood pressure rises which occur in quadriplegic spinal cord injury patients with automatic hyperreflexia. DESIGN Pressor dose responsiveness was evaluated by determining the steady-state dose of phenylephrine,(More)
OBJECTIVES To assess outcomes in patients with spinal cord injury (SCI) and a tracheostomy tube (TT), before and after the introduction of a tracheostomy review and management service (TRAMS) for ward-based patients. DESIGN Matched-pairs design with two cohorts, before and after the intervention. SETTING 900-bed tertiary hospital in Melbourne, Victoria.(More)
Ultrasound (US), a high-frequency acoustic energy traveling in the form of a mechanical wave, represents a potential site-specific intervention for osteoporosis. Bone is a dynamic tissue that remodels in response to applied mechanical stimuli. As a form of mechanical stimulation, US is anticipated to produce a similar remodeling response. This theory is(More)
Drawing from recent developments regarding the contextual nature of personality (e.g., D. Wood & B. W. Roberts, 2006), we conducted 2 studies (1 cross-sectional and 1 longitudinal over 1 year) to examine the validity of work personality in predicting job satisfaction and its mediation of the effect of global personality on job satisfaction. Study 1 showed(More)
Two patients with severe dialysis osteomalacia, whose fractures and deformities had become progressively worse over 3 years, were treated with desferrioxamine (DFO). They improved rapidly and over 6 months were able to stop taking analgesics and return to normal activities. Pre-treatment bone biopsy samples contained extensive osteoid covering trabecular(More)