Douglas Hugh James

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Historically, it has been assumed that the first-order envelope statistics of ultrasonic backscatter from myocardium are best described by the Rayleigh probability distribution function (PDF); however, few studies have tested this assumption. This study compares the ability of five PDFs, including the Rayleigh, to describe high-frequency (5-15 MHz)(More)
This study was performed to investigate the two-dimensional unprocessed radiofrequency (rf) ultrasonic backscatter from myocardium throughout the cardiac cycle. Eleven mongrel dogs underwent left lateral thoracotomy and had two-dimensional echocardiographic studies performed using a 5 MHz transducer. Regions of interest, selected to encompass a portion of(More)
A previously healthy 42-year-old woman developed severe dyspnea, chest discomfort, and malaise several hours after prolonged exposure to concentrated vapors from mineral spirits. On the way to the hospital, she sustained a cardiopulmonary arrest; on arrival several minutes later, she was found to be in ventricular fibrillation and was resuscitated. Her(More)
The effect of vincristine sulfate (VCR)2 on the incorporation of isotopic precursors into protein, RNA, and DNA of the pro tozoan Tetrahymena pyriformis has been studied. DNA synthesis in logartithmically growing cells of T. pyriformi.s was almost completely inhibited by concentrations of VCR which only moderately depressed RNA and protein synthesis. Under(More)
OBJECTIVE For many common conditions, such as unstable angina pectoris (UAP) in the elderly, the course of the disease and the influence of treatments on outcome need to be better described. In this report the authors demonstrate how a simple pocket-sized card system can be used by busy clinicians to identify patient cohorts and follow the courses of their(More)
Portraits are underused in the medical biographies of patients, yet they can illuminate health concerns and even health itself in many ways. Tying portraiture and medicine together analytically yields many insights into Pope's medical biography - from his response to satirical ridicule to his friends' concern for his health - without abandoning his(More)