Douglas Helman

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Declaration Hereby I certify that the thesis has been written by me. Any help that I have received in my research work has been acknowledged. Additionally, I certify that I have not used any auxiliary sources and literature except those cited in the thesis. Abstract Because of the simplicity in the structure of the Description Logic (DL) FL 0 , it has been(More)
A new analogue of recombinant human growth hormone (hGH), hGH des(1-6,14) was expressed in Escherichia coli, refolded and purified to homogeneity. The mutation decreased the hormone's ability to bind lactogenic and somatogenic receptors through its site 1, and almost completely abolished its ability to bind these receptors through site 2, as evidenced by(More)
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