Douglas G Manuel

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OBJECTIVE The definition of obesity (BMI ≥ 30 kg/m(2)), a key risk factor of diabetes, is widely used in white populations; however, its appropriateness in nonwhite populations has been questioned. We compared the incidence rates of diabetes across white, South Asian, Chinese, and black populations and identified equivalent ethnic-specific BMI cutoff values(More)
BACKGROUND In 2000, Ontario, Canada, initiated a universal influenza immunization program (UIIP) to provide free influenza vaccines for the entire population aged 6 mo or older. Influenza immunization increased more rapidly in younger age groups in Ontario compared to other Canadian provinces, which all maintained targeted immunization programs. We(More)
BACKGROUND Although people of South Asian, Chinese and black ethnic backgrounds represent about 60% of the world's population, most knowledge of cardiovascular risk is derived from studies conducted in white populations. We conducted a large, population-based comparison of cardiovascular risk among people of white, South Asian, Chinese and black ethnicity(More)
OBJECTIVE To estimate the burden of illness from diabetes using a population health survey linked to a population-based diabetes registry. RESEARCH DESIGN AND METHODS Measures of health-related quality of life (HRQOL) from the 1996/97 Ontario Health Survey (n = 35,517) were combined with diabetes prevalence and mortality data from the Ontario Diabetes(More)
BACKGROUND AND OBJECTIVES Validation of health administrative data for identifying patients with different health states (diseases and conditions) is a research priority, but no guidelines exist for ensuring quality. We created reporting guidelines for studies validating administrative data identification algorithms and used them to assess the quality of(More)
AIM To examine neighbourhood income differences in deaths amenable to medical care and public health over a 25-year period after the establishment of universal insurance for doctors and hospital services in Canada. METHODS Data for census metropolitan areas were obtained from the Canadian Mortality Database and population censuses for the years 1971,(More)
BACKGROUND Computer simulation models are used increasingly to support public health research and policy, but questions about their quality persist. The purpose of this article is to review the principles and methods for validation of population-based disease simulation models. METHODS We developed a comprehensive framework for validating population-based(More)
In early 2002, the Canadian Institutes of Health Research, Institute of Population and Public Health (CIHR-IPPH), with the advice of a multi-agency working group, embarked on a review of the literature to examine the issues and barriers related to Canadian population and public health (PPH) knowledge generation, dissemination and exchange, and uptake. The(More)
BACKGROUND Whether influenza vaccination is associated with Guillain-Barré syndrome (GBS) remains uncertain. METHODS We conducted 2 studies using population-based health care data from the province of Ontario, Canada. In the first study, we used the self-matched case-series method to explore the temporal association between probable influenza vaccination(More)
BACKGROUND There is growing evidence that cardiovascular risk profiles differ markedly across Canada's 4 major ethnic groups, namely White, South Asian, Chinese, and Black; however, the impact of long-term Canadian residency on cardiovascular risk within and across these ethnic groups is unknown. METHODS Using pooled data from Statistics Canada's National(More)