Douglas G Hughes

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Choroid plexus carcinoma (CPC) is a rare tumour occurring in childhood. The MRI features are not well described. To characterise the MRI features of CPC in children and to describe the role of MRI in post-surgical management. The pre- and post-operative MRI examinations of five children with histologically proven CPC treated at this hospital were reviewed.(More)
In order to investigate the relationship between pituitary appearance and the diagnosis of growth hormone deficiency (GHD), we have assessed magnetic resonance imaging (MRI) scans and GH status during provocation tests in 110 patients (78 males; median age 9.8, range 0.1-20 yr), evaluated for possible GH disorders. On the basis of pituitary function tests,(More)
A developmental venous anomaly is a congenital abnormality of venous drainage generally without clinical significance. The term Developmental Venous Anomaly [DVA] was first suggested by Lasjaunias et al. [7] to underline its character as an embryological variant of normal venous drainage. DVAs represent extreme variations of hemispheric white matter and(More)
Popliteal cysts are soft fluid-filled lesions of synovial origin which result from extrusion of joint fluid into the gastrocnemiosemimembranous bursa. They may occur in any age group, but 22–33% occur in the first 15 years of life. In this age group they are rarely associated with intraarticular abnormalities and therefore rarely require treatment. This(More)
The type II histamine receptor antagonists, cimetidine and ranitidine, widely used in treatment of peptic ulcer disease have been reported to cause bradycardia. To evaluate the cardiovascular effects of H2 antagonists nineteen healthy volunteers were entered into a double-blind crossover comparison of cimetidine 300 mg qid, ranitidine 150 mg bid, and(More)
Arteriovenous fistulas can rarely occur in patients with neurofibromatosis type 1. These lesions typically result from traumatic insult to the dysplastic parent artery. The damaged artery forms abnormal connections with nearby paraspinal and epidural venous structures. Surgical treatment of these lesions can be extremely challenging given the proximity to(More)
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