Douglas Friedman

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gamma-Aminobutyric acid (GABA) is a major inhibitory neurotransmitter in the mammalian retina, where it serves many roles in establishing complex response characteristics of ganglion cells. We now provide biochemical and physiological evidence that at least three subclasses of GABA receptors (A1, A2, and B) contribute to different types of synaptic(More)
Glycans 1 form one of the four basic classes of macromolecules in living systems, along with nucleic acids, proteins, and lipids. They are composed of individual sugar units that can be linked to one another in multiple ways, enabling them to form complex three-dimensional structures. All living cells are coated on their cell membranes with glycans or(More)
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