Douglas B Wilhite

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PURPOSE Patients with lower-extremity peripheral arterial disease (PAD) face a high risk of cardiovascular morbidity and mortality. Platelet inhibition (PI) significantly reduces this risk. Combination PI is common and increasingly indicated in patients with PAD; however, the effect on platelet function has not been objectively evaluated. Aspirin (ASA),(More)
Tissue factor (TF) is the physiological initiating mechanism for blood coagulation. Platelets play an important role in monocyte TF expression, thrombosis and inflammation. Aspirin, clopidogrel and cilostazol, which inhibit platelet responses by different mechanisms, are widely used in patients with arterial diseases. We tested the hypothesis that(More)
BACKGROUND A greater emphasis has recently been placed on laboratory-based training of core surgical skills and tasks, such as vascular anastomosis. Despite this emphasis, little objective data exist regarding the effectiveness of vascular anastomosis instruction in the laboratory setting. METHODS Residents of all postgraduate levels received(More)
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