Doug W. Mahoney

Learn More
Urinary exosome-like vesicles (ELVs) are a heterogenous mixture (diameter 40-200 nm) containing vesicles shed from all segments of the nephron including glomerular podocytes. Contamination with Tamm-Horsfall protein (THP) oligomers has hampered their isolation and proteomic analysis. Here we improved ELV isolation protocols employing density centrifugation(More)
OBJECTIVE Most patients with constrictive pericarditis have normal measures of left ventricular function when assessed by the ejection phase index of ejection fraction, yet there is a wide spectrum of outcome after pericardiectomy. We hypothesized that parameters of non-ejection indexes of cardiac function (+dP/dt and tau) may predict postoperative(More)
The purpose of this study was to provide a descriptive analysis of an inpatient amputee program at Spaulding Rehabilitation Hospital (SRH) in Boston; the analysis focused on nursing diagnoses and interventions documented in the medical record. The study was based on a retrospective chart review conducted for 96 inpatient lower-extremity amputees who were(More)
Time series models have been applied to forecast the market trends. Simple exponential smoothing (SES) method was one of them widely used as a forecasting tool in time series data. In this method, a smoothing parameter needs to be chosen in such a way tO minimize sums of squares forecast errors. By deriving the equivalence of the smoothing equation and the(More)
  • 1