Doug W. Mahoney

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OBJECTIVE Most patients with constrictive pericarditis have normal measures of left ventricular function when assessed by the ejection phase index of ejection fraction, yet there is a wide spectrum of outcome after pericardiectomy. We hypothesized that parameters of non-ejection indexes of cardiac function (+dP/dt and tau) may predict postoperative(More)
Urinary exosome-like vesicles (ELVs) are a heterogenous mixture (diameter 40-200 nm) containing vesicles shed from all segments of the nephron including glomerular podocytes. Contamination with Tamm-Horsfall protein (THP) oligomers has hampered their isolation and proteomic analysis. Here we improved ELV isolation protocols employing density centrifugation(More)
The purpose of this study was to provide a descriptive analysis of an inpatient amputee program at Spaulding Rehabilitation Hospital (SRH) in Boston; the analysis focused on nursing diagnoses and interventions documented in the medical record. The study was based on a retrospective chart review conducted for 96 inpatient lower-extremity amputees who were(More)
Time series models have been applied to forecast the market trends. Simple exponential smoothing (SES) method was one of them widely used as a forecasting tool in time series data. In this method, a smoothing parameter needs to be chosen in such a way tO minimize sums of squares forecast errors. By deriving the equivalence of the smoothing equation and the(More)
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