Doug Payne

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A population-based field study was conducted in Zanzibar Town, Zanzibar, Tanzania, to assess the in-vivo and in-vitro susceptibility to chloroquine of Plasmodium falciparum. Single-dose therapy with chloroquine (10 mg base/kg) failed to clear parasitaemia in 11 of 22 (50%) treated subjects, and a standard therapeutic regimen of chloroquine (25 mg base/kg)(More)
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