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OBJECTIVE To identify environmental factors involved in the etiology of insulin-dependent diabetes mellitus (IDDM). RESEARCH DESIGN AND METHODS An estimated 90% of all incident cases of IDDM in patients 0-14 years of age in New South Wales, Australia, were ascertained over 18 months. For each IDDM patient, two age- and sex-matched control subjects were(More)
Between 1976 and 1980, data were collected for a case-comparison study of laryngeal cancer in white males aged 30-79 years in six Texas counties using all histologically confirmed incident cases and a population-based comparison group. Dietary interviews were obtained from 151 living cases and 178 living comparison subjects. A significant inverse(More)
A double-blind, placebo-controlled, randomized, factorial study using a daily oral administration of 30 mg beta-carotene and/or 500 mg vitamin C was conducted in 141 women with colposcopically and histologically confirmed minor squamous atypia or cervical intra-epithelial neoplasia (CIN) I. Over approximately 2 years of follow-up, 43 lesions regressed to(More)
PURPOSE Dietary patterns offer an alternative method for analyzing dietary intakes that take into account the whole diet. We investigated empirical dietary patterns and prostate cancer risk in Western Australia (WA) using a population-based case-control study. METHODS Incident prostate cancer cases were identified via the WA Cancer Registry. Controls were(More)
OBJECTIVE To study the effect of vitamin A supplementation on morbidity and mortality from infectious disease. DESIGN A meta-analysis aimed at identifying and combining mortality and morbidity data from all randomised controlled trials of vitamin A. RESULTS Of 20 controlled trials identified, 12 trials were randomised trials and provided "intention to(More)
The similarities and differences in four methods for adjusting nutrient intake for energy intake are discussed. The situation for macronutrients, as exemplified by fat intake, is compared to the situation for micronutrients such as vitamin C, with the conclusion that different methods are appropriate for the two situations. The categorization of data in(More)
OBJECTIVES To describe the prevalence of markers of growth, chronic and infectious disease in peripubertal Aboriginal children living in the Darwin Health Region in the "Top End" of the Northern Territory, and to compare prevalence between children living in urban and remote areas. DESIGN Cross-sectional survey nested in a prospective birth cohort. (More)
OBJECTIVES To compare a widely used Australian food-frequency questionnaire (FFQ) with diet records and consider the results in relation to its use in nutrition surveillance. DESIGN Inter-method reliability study. SETTING A randomised trial in subjects with past asbestos exposure. SUBJECTS Seventy-two adults living in Western Australia. METHODS A(More)
BACKGROUND It is thought that vitamin E may improve tolerance to intermittent claudication (i.e. pain caused by ischaemia in the muscles of the leg during exercise), thereby relieving the pain, through a variety of mechanisms. OBJECTIVES The objective of this review was to determine the effects of vitamin E on people with intermittent claudication. (More)
OBJECTIVES To investigate dietary patterns and food intake as risk factors for surgically treated benign prostatic hyperplasia (BPH), as few risk factors have been established for BPH and recently there has been some interest in a role for diet in the development of BPH. PATIENTS, SUBJECTS AND METHODS A case-control study was conducted in Western(More)