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BACKGROUND Gonadotrophin releasing hormone (GnRH) analogues are widely used in IVF programmes as a method of suppressing the luteinizing hormone (LH) surge prior to ovarian stimulation, but their roles outside the pituitary remain relatively unknown. A 2002 Cochrane review (Al-Inany et al. Gonadotrophin-releasing hormone antagonists for assisted conception.(More)
OBJECTIVE To examine brain-stem auditory function at term in very preterm infants who suffered chronic lung disease (CLD). METHODS Brain-stem auditory evoked response (BAER) was recorded at term with clicks in 25 very preterm infants with CLD and no concomitant other major perinatal problems. RESULTS Compared to those in normal term controls, BAER wave(More)
Relative maturation of peripheral and central regions of the neonatal brainstem was studied using brainstem auditory evoked responses in 174 healthy preterm infants (gestational age 30-36 wk). From 30- to 42-wk postconceptional age (PCA), I-III and III-V intervals shortened with increasing age. It was difficult to detect any apparent differences in(More)
AIM To clarify further the influence of intrauterine growth retardation (IUGR) on early neural development. METHODS In 30 small-for-gestational age (SGA) preterm infants at term, brainstem auditory-evoked responses (BAERs) were recorded with clicks of different repetition rates. All infants had a birthweight < 3rd centile, without any other major(More)
AIM To examine the process of change in hearing threshold during the neonatal period after perinatal hypoxia-ischaemia. METHODS The threshold of brainstem auditory evoked responses (BAER) was measured serially during the first month after birth in 92 term babies who suffered hypoxia-ischaemia. RESULTS The mean BAER threshold in these babies was(More)
Auditory neural responses to acoustic stimuli of different rates were studied by analyzing changes in brainstem auditory evoked responses (BAER) with increasing repetition rate of clicks, or rate-dependent changes, in 62 very preterm babies (gestation 24-32 wk). None had perinatal asphyxia or major complications at the time of testing (37-42 wk(More)
Functional integrity of the auditory brainstem was studied at term in babies born at 30-36 wk of gestation using maximum length sequence brainstem auditory evoked response (MLS BAER). Compared with normal term babies, preterm babies who had perinatal complications showed a tendency of an increase in wave V latency and I-V and III-V intervals at all 91-910/s(More)
UNLABELLED This study examined whether high presentation rates of clicks while recording brainstem auditory evoked responses (BAER) can improve the detection of central auditory impairment in asphyxiated neonates using the BAER. The BAER was analysed at different presentation rates of clicks within the first week after birth in 38 term neonates who suffered(More)
OBJECTIVES To assess functional integrity of the auditory brainstem in neonates with transient low Apgar scores. METHODS Forty-two term infants were studied with brainstem auditory evoked response (BAER) using the maximum length sequence during the first month of life. All had transient low Apgar scores but no clinical signs of hypoxic-ischaemic(More)
Maximum length sequence brainstem auditory evoked response (BAER) was studied within the first week after birth in 28 term neonates who had perinatal hypoxia-ischemia, or asphyxia. In the BAER recorded using conventional averaging techniques (click rate 21/s), the only abnormality was a slight increase in III-V interval, in addition to an increase in wave(More)