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- Anna Köttgen, Carsten Alexander Böger, +128 authors Caroline Fox
- Nature Genetics
- 2010
Chronic kidney disease (CKD) is a significant public health problem, and recent genetic studies have identified common CKD susceptibility variants. The CKDGen consortium performed a meta-analysis of… (More)
- Hans L. Hillege, Dorothea D M Nitsch, +10 authors Dirk Jan van Veldhuisen
- Circulation
- 2006
BACKGROUND
Decreased renal function has been found to be an independent risk factor for cardiovascular outcomes in patients with chronic heart failure (CHF) with markedly reduced left ventricular… (More)
- Andrew G Hall, Bruce M. Hendry, Dorothea D M Nitsch, John O. Connolly
- American journal of kidney diseases : the…
- 2011
Tenofovir (TDF) is an effective and widely used treatment for both human immunodeficiency virus (HIV) and hepatitis B virus infection. Although studies suggest that TDF has a low overall toxicity… (More)
- Gita Devi Mishra, Dorothea D M Nitsch, Stephanie V. Black, Bianca L De Stavola, Diana Kuh, Rebecca Hardy
- International journal of epidemiology
- 2009
BACKGROUND
There is growing interest in the relationship between time spent in adverse circumstances across life course and increased risk of chronic disease and early mortality. This accumulation… (More)
- Dorothea D M Nitsch, Morgan E Grams, +12 authors Brenda R. Hemmelgarn
- BMJ
- 2013
OBJECTIVE
To assess for the presence of a sex interaction in the associations of estimated glomerular filtration rate and albuminuria with all-cause mortality, cardiovascular mortality, and end stage… (More)
- Katharina Brück, Vianda S. Stel, +26 authors Kitty J. Jager
- Journal of the American Society of Nephrology…
- 2016
CKD prevalence estimation is central to CKD management and prevention planning at the population level. This study estimated CKD prevalence in the European adult general population and investigated… (More)
- Guy Hume Neild, Glen T. D. Thomson, Dorothea D M Nitsch, Robin G. Woolfson, John O. Connolly, Christopher R J Woodhouse
- BMC nephrology
- 2004
BACKGROUND
The commonest cause of end-stage renal failure (ESRF) in children and young adults is congenital malformation of the kidney and urinary tract. In this retrospective review, we examine… (More)
- Dorothea D M Nitsch, Mariam Molokhia, Liam Smeeth, Bianca DeStavola, John C. Whittaker, David A Leon
- American journal of epidemiology
- 2006
"Mendelian randomization" refers to the random assortment of genes transferred from parent to offspring at the time of gamete formation. This process has been compared to a randomized controlled… (More)
- Paul J Roderick, Richard J Atkins, +4 authors C. J. Bulpitt
- Age and ageing
- 2008
BACKGROUND
national policy is focused on early identification, referral and management of chronic kidney disease (CKD) to prevent both progression to endstage renal failure and cardiovascular… (More)
- Paul J Roderick, Richard J Atkins, +5 authors Astrid Elizabeth Fletcher
- American journal of kidney diseases : the…
- 2009
BACKGROUND
The prevalence of chronic kidney disease (CKD) increases with age; however, the prognostic significance in older people is uncertain. This study aims to determine the association of CKD… (More)