Dorothée Deppe

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Using genetic engineering a humanized Fab fragment with specificity for CD19 was fused to a disulfide-stabilized single-chain antibody (dsFv) recognizing CD5. This format should show reduced immunogenicity and improved tissue penetration. The specificity of bsAb FabCD19xdsFvCD5 binding to target cells was verified by flow cytometry on B and T lymphoma cell(More)
The Epidemiology and Laboratory Cooperative is an agreement that provides state and large local health departments with resources to strengthen and enhance basic capacity for public health surveillance and response for infectious diseases. The funding is used to implement new technology, upgrade systems, train staff, and purchase office and laboratory(More)
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