Dorit Hockman

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Comparative embryology expands our understanding of unique limb structures, such as that found in bats. Bat forelimb digits 2 to 5 are differentially elongated and joined by webbing, while the hindlimb digits are of similar length in many species. We compare limb development between the mouse and the Natal long-fingered bat, Miniopterus natalensis, to(More)
Sonic hedgehog (Shh) plays an integral role in both the anterior-posterior (A-P) patterning and expansion of developing vertebrate limbs through a feedback loop involving Fgfs, Bmps, and Gremlin. In bat limbs A-P patterning and the size of the digital field are unique. The posterior digits of the forelimb are elongated and joined by tissue, whereas the(More)
The postembryonic antennal development and life cycle of a member of the insect order Mantophasmatodea (Lobatophasma redelinghuysense) was investigated using a series of annulus counts and a time sequence of head capsule measurements. The life cycle comprised six instars. Females achieved significantly larger head capsules from instar 2 onwards, resulting(More)
The bat has strikingly divergent forelimbs (long digits supporting wing membranes) and hindlimbs (short, typically free digits) due to the distinct requirements of both aerial and terrestrial locomotion. During embryonic development, the morphology of the bat forelimb deviates dramatically from the mouse and chick, offering an alternative paradigm for(More)
Did segmented body plans evolve just once, or repeatedly among the animals? This question has become all the more controversial , now that molecular phylogenetic trees make it clear that the three major clades of segmented animals, vertebrates, annelids and the pan-arthropoda, each lies within a different major clade of the animals. If we are to have any(More)
Cranial neurogenic placodes and the neural crest make essential contributions to key adult characteristics of all vertebrates, including the paired peripheral sense organs and craniofacial skeleton. Neurogenic placode development has been extensively characterized in representative jawed vertebrates (gnathostomes) but not in jawless fishes (agnathans).(More)
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