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Slowly progressing coronary artery stenosis leading to complete occlusion within about 3 weeks was produced in dogs. Within this time collateral vessels had enlarged sufficiently to prevent myocardial infarction. Early, intermediate, and late (1 year after occlusion) stages of collateral development were studied with the scanning and transmission electron(More)
Pretreatment of strips of rabbit aorta with 10(-3) M sodium cyanide reduced contractions to 10(-8) through 10(-4) M norepinephrine (NE) added cumulatively. This antagonism by cyanide was not altered by 4 X 10(-6) M ouabain or verapamil, suggesting a lack of involvement of Na+, K+ ATPase or of calcium influx in the antagonism. Cyanide potentiated(More)
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